teichoplanine, azithromycin and ciprofloxacin) and antimicrobial cationic peptides (AMPs;
نویسندگان
چکیده
منابع مشابه
A Novel Defensin-Like Peptide Associated with Two Other New Cationic Antimicrobial Peptides in Transcriptome of the Iranian Scorpion Venom
Introduction: Scorpion venom is a source of bioactive peptides, and some antimicrobial peptides (AMPs) have been found in the venom gland of scorpions. Therefore, the discovery of new anti-infective agents is an essential need to overcome the problem of antibiotic resistance of clinical isolates. Here, we describe three new cationic AMPs, including meuVAP-6, meuAP-18-1, and meuPep34 from the ve...
متن کاملExpression and antimicrobial activity analysis of dermaseptin B1 recombinant peptides in tobacco transgenic plants
Recently, new molecular breeding and genetic engineering approaches have emerged to overcome the limitations of conventional breeding methods in generating disease-resistance transgenic plants. The use of antimicrobial peptides (AMPs) to produce transgenic plants resistant to a wide range of plant pathogens has achieved great success. Among huge number of AMPs, Dermaseptin B1 (DrsB1), an antimi...
متن کاملInvestigating the Anticancer Activity of Some Cationic Antimicrobial Peptides in Epithelial Tumor Cells
Cationic antimicrobial peptides (AMPs) became a promising alternative to the conventional cancer drugs. We investigated the effects of 5 AMPs (melittin, galanin-mastoparan, cecropins A, B and P1) on the viability of HT-29 and AR-42J carcinoma cells. The viability of the cells was evaluated and used to calculate the AMPs therapeutic index. Also, cellular apoptosis and necrosis were analyzed. Mel...
متن کاملA Novel Defensin-Like Peptide Associated with Two Other New Cationic Antimicrobial Peptides in Transcriptome of the Iranian Scorpion Venom
INTRODUCTION Scorpion venom is a source of bioactive peptides, and some antimicrobial peptides (AMPs) have been found in the venom gland of scorpions. Therefore, the discovery of new anti-infective agents is an essential need to overcome the problem of antibiotic resistance of clinical isolates. Here, we describe three new cationic AMPs, including meuVAP-6, meuAP-18-1, and meuPep34 from the ven...
متن کاملDesign and synthesis of cationic antimicrobial peptides with improved activity and selectivity against Vibrio spp.
Extensive use of classical antibiotics has led to the growing emergence of many resistant strains of pathogenic bacteria. Evidence has suggested that cationic antimicrobial peptides (AMPs) are of greatest potential to represent a new class of antibiotics. The largest group of AMPs comprises peptides that fold into an amphipathic alpha-helical conformation when interacting with the target microo...
متن کامل